Evidence map›Paper›PMID 42338999›Full record

ReviewCardiac failure review2026

Valvular Heart Disease in Heart Failure with Preserved Ejection Fraction.

Athena Adeli, Revathy Sampath-Kumar, Anne Wang, Aristomenis Manouras, Gianluigi Savarese, Rebecca T Hahn, Lars H Lund, Bahira Shahim

Abstract readReview
In one paragraph

Review in Cardiac failure review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Athena AdeliDivision of Cardiology, Department of Medicine, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4132-0388
Revathy Sampath-KumarDivision of Cardiovascular Medicine, University of California San Diego La Jolla, CA, US.ORCID https://orcid.org/0000-0001-5913-1548
Anne WangDivision of Cardiology, Department of Medicine, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0002-4047-7730
Aristomenis ManourasDivision of Cardiology, Department of Medicine, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0002-6617-2070
Gianluigi SavareseDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7732-0887
Rebecca T HahnDepartment of Medicine, Columbia University Irving Medical Center New York, NY, US.ORCID https://orcid.org/0000-0003-1342-9191
Lars H LundDivision of Cardiology, Department of Medicine, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0003-1411-4482
Bahira ShahimDivision of Cardiology, Department of Medicine, Karolinska Institutet Stockholm, Sweden.ORCID https://orcid.org/0000-0001-5688-6101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure with preserved ejection fraction (HFpEF) is associated with reduced functional capacity and quality of life, as well as with high rates of heart failure hospitalisation and mortality. Valvular heart disease (VHD) is frequently encountered in patients with HFpEF, and both conditions share common risk factors, such as age, hypertension, diabetes and coronary artery disease, which may contribute to their shared pathogenesis and progression. With recent advances in percutaneous therapies for VHD and an improved understanding of HFpEF, there is a growing interest in the relationship between VHD and HFpEF. In this review, we provide an overview of the pathophysiology, epidemiology and management strategies of tricuspid regurgitation, mitral regurgitation, aortic stenosis and aortic regurgitation in the setting of HFpEF.

Indexed as

aortic regurgitationaortic stenosisepidemiologyHFpEFmitral regurgitationtricuspid regurgitation

Identifiers

PMID42338999
PMCPMC13284787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.