Evidence map›Paper›PMID 42338725›Full record

ArticleFrontiers in cardiovascular medicine2026

Postoperative S100B protein levels as a measure for predicting neurological deficit in children undergoing cardiac surgery.

Evyatar Hubara, Lital Kalich Philosoph, Simon Lassman, Yelena Skourikhin, Rina Hemi, Omer Bar-Yosef

Abstract read
PubMed Full text at PMC Publisher
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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Evyatar HubaraPediatric Cardiac Intensive Care Unit (PCICU), Edmond and Lily Safra Children's Hospital, Sheb, Ramat Gan, Israel.
Lital Kalich PhilosophWeinberg Child Development Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Simon LassmanPediatric Neurology, Sheba Medical Center, The Edmond and Lily Safra Children's Hospital, Ramat Gan, Israel.
Yelena SkourikhinPediatric Cardiac Intensive Care Unit (PCICU), Edmond and Lily Safra Children's Hospital, Sheb, Ramat Gan, Israel.
Rina HemiEndocrine Laboratory Institute of Endocrinology, Sheba Medical Center, Ramat Gan, Israel.
Omer Bar-YosefWeinberg Child Development Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain injury following congenital heart surgery is associated with long-term neurodevelopmental deficits. Early identification of such injury may guide timely neuroprotective interventions. The calcium-binding protein S100B has been established in retrospective studies to be associated with poor neurological outcomes after surgery. These findings suggest that S100B may serve as a biomarker of central nervous system injury. Our study prospectively investigates the predictive value of S100B as a marker for new neurological deficits (NND) in infants undergoing cardiac surgery. In a prospective cohort of 130 infants undergoing congenital heart surgery, S100B was sampled before (

Indexed as

biomarkerbraincongenital-heart-defectinjuryneurologyS100B

Identifiers

PMID42338725
PMCPMC13284042

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.