Evidence map›Paper›PMID 42338687›Full record

ArticleAccess microbiology2026

Effect of sialidase inhibitors on a plaque community biofilm model.

Chandra Ramalingam, Katherine Ansbro, Jonathan Pratten, David Bradshaw, Graham P Stafford

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Access microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chandra RamalingamSchool of Clinical Dentistry, University of Sheffield, Sheffield, S10 2TA, UK.ORCID https://orcid.org/0000-0003-0487-9991
Katherine AnsbroSchool of Clinical Dentistry, University of Sheffield, Sheffield, S10 2TA, UK.
Jonathan PrattenOral health R&D, Haleon, Weybridge, K13 0DE, UK.
David BradshawOral health R&D, Haleon, Weybridge, K13 0DE, UK.
Graham P StaffordSchool of Clinical Dentistry, University of Sheffield, Sheffield, S10 2TA, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral microbiome is a diverse ecosystem that plays a critical role in health and disease and contains numerous bacterial species capable of metabolizing host-derived glycans, particularly sialic acids. Sialidase enzymes can be produced by both commensal and pathogenic bacteria influencing biofilm formation and host interactions. To investigate how sialidase activity might influence the oral microbiome, we conducted a series of

Indexed as

16S sequencingmicrobiomeMiSeqONTsialidase

Identifiers

PMID42338687
PMCPMC13286422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.