ReviewRSC chemical biology2026
DNA origami-based drug delivery and cell manipulation: toward intelligent nanomedicine.
Review in RSC chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA origami has emerged as a versatile platform for constructing nanoscale architectures with precise shape programmability, molecular-level addressability, and dynamic structural reconfigurability. Since its introduction, DNA origami has evolved from a structural design method into a functional nanosystem capable of integrating molecular recognition, logic-gated operations, and mechanical motion, enabling a wide range of biomedical applications. This review outlines recent advances in DNA origami-based drug delivery and the regulation of cellular functions and cell fate. Strategic control over size, shape, and mechanical properties is discussed in the context of cellular uptake, intracellular behavior, and the efficient delivery of small-molecule drugs and nucleic acid therapeutics. Recent progress in dynamic DNA origami nanodevices and nanorobots that respond to molecular, chemical, or physical cues is highlighted, including systems that enable spatiotemporally controlled payload release and the nanoscale organization of membrane receptors to modulate cellular signaling. In addition, key stabilization strategies required for
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.