ArticleiScience2026
Multi-organ acute and delayed effects following exposure to neutron radiation.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
16 authors.
Funding
Abstract
Neutron radiation exposure is a life-threatening consequence of nuclear disasters. To determine the effect of high dose neutron exposures on late responding organs, we assessed survival and characterized organ-specific injuries in adult male and female rats exposed to whole-body 2-10 Gy high linear energy transfer fast neutrons with 5%-8% bone marrow shielding. Survival through the acute and delayed sequelae of organ radiation injury was monitored for 1 year. Longitudinal secondary outcomes, including body weight, hematology, respiration, blood urea nitrogen, urinary proteomics and metabolomics, and cataract formation were assessed. During the acute sequelae of gastrointestinal and hematopoietic injury, neutron irradiation was 1.5-1.6 times more damaging than equivalent doses of X-ray. For late-responding organs, the relative biological effect of neutrons was 1.6 for the lung and 1.3 for the kidney. Urine proteomic and metabolomic profiles exhibited a time- and dose-dependent dysregulation. Altered proteins were associated with oxidative stress and renal injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.