Evidence map›Paper›PMID 42338464›Full record

ReviewNeuro-oncology advances2026

Executive function after childhood cancer: Insights from network neuroscience.

Katie Wade Alonso, Donald J Mabbott

Abstract readReview
In one paragraph

Review in Neuro-oncology advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katie Wade AlonsoThe Department of Psychology, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0002-3343-9170
Donald J MabbottThe Department of Psychology, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-6161-5066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we examine the empirical literature on the cognitive late effects of childhood acute lymphoblastic leukemia (ALL) and brain tumors, with a focus on executive function and its neural underpinnings. Executive function is a critical domain, influencing survivors' educational attainment, social relationships, and overall quality of life. We first examine behavioral evidence of executive function impairments observed after cancer diagnosis and treatment. We then explore neuroscientific insights, integrating findings from volumetric analyses, functional imaging, and network-based approaches to uncover neural mechanisms underlying these deficits. Special emphasis is placed on the value of network-based methods, including structural and functional connectivity as well as overall network organization. Finally, we identify promising directions for future research aimed at deepening our understanding of these cognitive late effects and developing effective strategies to mitigate them. This review seeks to bridge behavioral and neural perspectives, offering insights that can inform clinical practices and improve outcomes for childhood cancer survivors.

Indexed as

childhood acute lymphoblastic leukemiachildhood brain tumorexecutive functionlate effectsnetwork neuroscience

Identifiers

PMID42338464
PMCPMC13284614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.