Evidence map›Paper›PMID 42338420›Full record

ArticleChemical communications (Cambridge, England)2026

Light-activated thiomaleimide crosslinking stabilizes collagen mimetic peptide triple helix.

Rafael A Castro, Shashika Gammanchiralage, Christopher Price, April M Kloxin

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rafael A CastroDepartment of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA. akloxin@udel.edu.ORCID http://orcid.org/0000-0003-2487-9550
Shashika GammanchiralageDepartment of Materials Science and Engineering, University of Delaware, 127 The Green, Newark, DE 19716, USA.
Christopher PriceDepartment of Biomedical Engineering, University of Delaware, 590 Avenue 1743, Newark, DE 19713, USA.
April M KloxinDepartment of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA. akloxin@udel.edu.ORCID http://orcid.org/0000-0002-4594-2953

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI POLENOVA, TATYANA · 2014 to 2018
$5.8M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Discovery of Chemical Probes and Therapeutic Leads: Thermo Exploris 240P30GM159572 · NIGMS · UNIVERSITY OF DELAWARE · PI JOSEPH M FOX · 2025 to 2026
$3.8M
Unraveling fibrosis with dynamic microenvironments and molecular toolsDP2HL152424 · NHLBI · UNIVERSITY OF DELAWARE · PI KLOXIN, APRIL M · 2019 to 2019
$2.4M
Collagen-mediated approaches to improve the local delivery and hypothermic release of osteoarthritis therapeuticsR01AR080707 · NIAMS · UNIVERSITY OF DELAWARE · PI Christopher Price · 2023 to 2026
$2.4M
Collagen-based targeting for improving delivery and efficacy of osteoarthritis drugsR21AR069778 · NIAMS · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L, PRICE, CHRISTOPHER · 2017 to 2018
$365k
NHLBI NIH HHS DP2 HL152424NIAMS NIH HHS R01 AR080707NIAMS NIH HHS R21 AR069778NIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM110758NIGMS NIH HHS P30 GM159572NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

Collagen mimetic peptides (CMPs) are useful self-assembling building blocks for creating tunable biomaterials with structure and function dependent on triple helix stability. We demonstrate rapid, UV-activated stabilization of a CMP triple helix

Indexed as

CollagenCross-Linking ReagentsLightMaleimidesPeptidesProtein Structure, SecondaryUltraviolet RaysCollagenCross-Linking ReagentsmaleimideMaleimidesPeptides

Identifiers

PMID42338420
PMCPMC13291891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.