Evidence map›Paper›PMID 42338238›Full record

ArticleJournal of computational chemistry2026

The Intricate Mechanism of Nitric Oxide Synthase.

Per E M Siegbahn

Abstract read
In one paragraph

Article in Journal of computational chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Per E M SiegbahnDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7787-1881

Funding

Stockholms Universitet
6 · The paper itself

Abstract

The biological formation of NO is performed by nitric oxide synthase. For the first half of the mechanism, a consensus understanding has been reached, but not for the second half. Several attempts to reach a mechanism in agreement with experimental observations have been reported, but without success. Therefore, another study of that half-reaction has been made here. The main difficulties have been to explain the observed non-stoichiometric action of the cofactor H

Indexed as

Nitric Oxide SynthaseElectron TransportHemeNitric OxideOxidation-ReductionHemeNitric OxideNitric Oxide Synthase

Identifiers

PMID42338238
PMCPMC13291759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.