Evidence map›Paper›PMID 42338170›Full record

ArticleThe Medical journal of Australia2026

Worsening Asthma Outcomes in Australian Adults: A Comparison of Stratified Sample Surveys in 2012 and 2021.

Helen K Reddel, Maria R Ampon, Leanne M Poulos, Sharon R Davis, Brett G Toelle, Guy B Marks, Taehoon Lee

Abstract readComparative Study
In one paragraph

Article in The Medical journal of Australia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helen K ReddelAustralian Centre for Airways Disease Monitoring (ACAM), Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6695-6350
Maria R AmponAustralian Centre for Airways Disease Monitoring (ACAM), Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Leanne M PoulosAustralian Centre for Airways Disease Monitoring (ACAM), Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Sharon R DavisAustralian Centre for Airways Disease Monitoring (ACAM), Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Brett G ToelleRespiratory and Environmental Epidemiology, Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Guy B MarksRespiratory and Environmental Epidemiology, Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Taehoon LeeAustralian Centre for Airways Disease Monitoring (ACAM), Woolcock Institute of Medical Research, Sydney, New South Wales, Australia.

Funding

AstraZeneca AustraliaChiesi FarmaceuticiGlaxoSmithKline AustraliaNational Health and Medical Research CouncilSanofi Australia
6 · The paper itself

Abstract

objectivesTo report patterns of asthma control, medications and healthcare utilisation in Australian adults with asthma in 2021, and assess changes since a similar survey in 2012. STUDY TYPE: Cross-sectional web-based survey (February-March 2021; n = 5427), compared with a similar 2012 survey (n = 2686). SETTING/

participantsAdults (≥ 18 years) with asthma, recruited from large web-based panels, with enrolment stratified by age group, gender and state/territory.

main outcome measuresAsthma control test (ACT), healthcare utilisation and medications.

resultsMedian age was 46 years; 59% of participants reported female gender. Compared with 2012, fewer participants had well-controlled symptoms (ACT ≥ 20: 2021, 48.0%; 2012, 54.4%; p < 0.001), and more had very poorly controlled symptoms (ACT 5-15: 2021, 26.8%; 2012, 22.9%; p < 0.001). Urgent asthma healthcare had increased (2021, 37.9%; 2012, 28.6%; odds ratio 1.53 [95% confidence interval, 1.37-1.69]; p < 0.001). Inhaled corticosteroid (ICS) use in the previous year was similar (2021, 60.9%; 2012, 60.8%) but adherence was lower (p < 0.001). Fewer participants had good symptom control while taking little/no ICS (2021, 33.4%; 2012, 40.1%), and more had uncontrolled symptoms with little/no ICS (2021, 38.1%; 2012, 25.6%; p < 0.001); among the latter group, urgent healthcare utilisation had increased (2021, 63.5%; 2012, 41.2%; p < 0.001). In 2021, 28.7% reported using oral corticosteroids for asthma in the previous year; only 42.0% of ICS users recalled their inhaler technique having been checked in the past 12 months. Overuse of short-acting beta

conclusionOur comparison of these two large nationally stratified sample surveys demonstrates significant worsening of key asthma indicators between 2012 and 2021, including worse symptom control and urgent healthcare use, but also indicates opportunities for improvement. The findings highlight an urgent need for system-wide implementation of the 2025 Australian asthma guidelines to reduce preventable morbidity.

trial registrationACTRN12620000977976p.

Indexed as

Anti-Asthmatic AgentsAsthmaPatient Acceptance of Health CareAdolescentAdrenal Cortex HormonesAdultAgedAustraliaCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAdrenal Cortex HormonesAnti-Asthmatic Agentsasthmahealth status indicatorssurveys and questionnairestreatment outcome

Identifiers

PMID42338170
PMCPMC13291629

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.