ArticleRenal failure2026
Cardiometabolic benefits of parathyroidectomy in dialysis patients with secondary hyperparathyroidism: preliminary insights from CT radiomics and body composition analysis.
Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Secondary hyperparathyroidism (SHPT) contributes to mineral-bone disorders, chronic inflammation, and adverse cardiometabolic outcomes in patients undergoing dialysis. Radiomics of epicardial adipose tissue (EAT) derived from computed tomography (CT) may serve as an imaging biomarker of cardiometabolic risk; however, the effect of parathyroidectomy (PTX) on EAT remodeling remains unclear. This cohort study enrolled dialysis patients with severe SHPT who underwent PTX and controls who received standard medical therapy. At baseline and 6 months, the participants underwent CT-based EAT radiomics assessment, coronary artery calcification (CAC) scoring, dual-energy X-ray absorptiometry (DEXA) for body composition and bone mineral density (BMD), and biochemical evaluation. PTX significantly decreased EAT attenuation (-69.99 ± 8.07 to -72.64 ± 5.68 HU;
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