ArticleMicrobiologyOpen2026
Antimicrobial Photodynamic Therapy With New Methylene Blue and Its Combined Effect With Antibiotics Against MDR Acinetobacter baumannii.
Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to evaluate the antibacterial efficacy of new methylene blue-mediated antimicrobial photodynamic therapy (NMB-mediated aPDT) in combination with tigecycline and colistin against multidrug-resistant (MDR) A. baumannii and to explore ROS production as a possible mechanism contributing to the enhanced antibacterial activity of the combined treatments. MIC determination, sublethal irradiation and aPDT assays, checkerboard analysis, and ROS detection were performed. MIC of NMB for this MDR strain was greater than 100 μg/mL. Under various radiation times, aPDT at 12.5 μg/mL NMB was considered a sublethal dose that represented with a reduction of 1.7-2.6 log
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.