ArticleChemistry (Weinheim an der Bergstrasse, Germany)2026
Fluorogenic Sydnones for Bioorthogonal Labeling of DNA.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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0 citing papers in PubMed.
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Authors and funding
2 authors.
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Abstract
Five cyanine-styryl dyes were synthetically conjugated to sydnones combining fluorogenicity with bioorthogonal reactivity. The synthesis was based on synthetic modules and building blocks using Heck couplings as central conjugation steps. The novel cyanine-styryl dyes show significant Stokes shifts to well separate excitation and emission for fluorescent cell imaging. Reaction kinetics and fluorogenicity of the strain-promoted sydnone-alkyne cycloaddition (SPSAC) with 7-deazadenosine, 7-deaza-2'-deoxyadenosine and DNA modified by bicyclo[6.1.0]non-4-yne (BCN) were investigated by spectroscopic means. The determined second-order rate constants k
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.