Evidence map›Paper›PMID 42337926›Full record

ArticleHealth economics2026

The Effects of Compulsory Licensing: A Case Study of HIV Drugs.

Nicolau Martin-Bassols, Miquel Serra-Burriel, Kerstin Noelle Vokinger

Abstract read
In one paragraph

Article in Health economics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicolau Martin-BassolsCenter for Economic and Social Research (CESR), University of Southern California, Los Angeles, California, USA.
Miquel Serra-BurrielEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-8595-1224
Kerstin Noelle VokingerFaculty of Law, University of Zurich and Department of Health Sciences and Technology, Academic Chair for Regulation in Law, Medicine, and Technology, ETH Zurich, Zürich, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
6 · The paper itself

Abstract

Compulsory licensing is a legal mechanism that allows governments the use of patented medicines without the owner's consent, subject to conditions and compensation, to meet public-health needs. Despite its policy relevance and increasing use, empirical evidence on its market effects remains limited. This study examines the association between compulsory licensing and the commercial accessibility and affordability of HIV medications across 11 countries from 2002 to 2022. We combine quarterly data on drug sales and prices from IQVIA with implementation dates from the TRIPS Flexibilities Database, focusing on 21 HIV drugs subject to at least one compulsory license. Using a staggered difference-in-differences design, we estimate the average treatment effect on the treated (ATT) of compulsory licensing on drug consumption and prices, under a parallel trends assumption. We find an economically meaningful increase in retail and hospital sales following the implementation of compulsory licenses, amounting to approximately 21% of a standard deviation in the countries that implemented them. In addition, we estimate a reduction in prices of approximately 19% of a standard deviation. These associations are consistent with compulsory licenses having contributed to improved availability of HIV drugs through commercial channels, with meaningful effects on prices. Our estimates do not capture-and therefore cannot rule out-potential additional effects on access via public importation or production, donations, or NGO-led supply chains.

Indexed as

Anti-HIV AgentsHIV InfectionsLicensureCommerceHealth Services AccessibilityHumansAnti-HIV Agentsantiretroviralscompulsory licensingessential medicinesHIVmarket access

Identifiers

PMID42337926
PMCPMC13532639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.