ArticleImplementation science : IS2026
Development and validation of a clinical practice guidelines implementability assessment tool (CPG-IAT) based on the COSMIN framework.
Article in Implementation science : IS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionWe define guideline implementability as the characteristics of the guideline that reflect the extent to which it is likely to be adopted in clinical practice. Improving the intrinsic quality (e.g., context, format, language etc.) of clinical practice guidelines (CPGs) may be a cost-effective and broadly applicable approach. This study was aimed to develop the clinical practice guidelines implementability assessment tool (CPG-IAT) and test its psychometric properties.
methodsThe study used the 2022 CPGs recorded in the STAR guideline repository as the evaluation sample. The evaluation team consisted of 60 members with clinical, guideline development, or prior rating experience, responsible for assessing the included guidelines. Guideline evaluation data were randomly assigned to be utilized for an exploratory factor analysis (n = 131) or for a confirmatory factor analysis (n = 130). Reliability and validity analyses were then conducted with the full sample.
resultsThe exploratory factor analysis resulted in a 16-item tool with four dimensions representing Methodological Rigor and Transparency, Recommendation Clarity and Interpretability, clinical relevance and actionability. Confirmatory factor analysis supported a priori factor structure. The tool demonstrated excellent internal consistency reliability, convergent validity, construct reliability, split-half reliability, test-retest reliability, inter-rater reliability and pragmatic.
conclusionsThe CPG-IAT provides a psychometrically validated instrument for assessing the intrinsic implementability of CPGs both during and after the guideline development process. The CPG-IAT contributes a systematically developed and empirically validated measure of guideline implementability, with potential to inform future research and practice aimed at enhancing the translation of evidence-based guidelines into clinical practice.
trial registrationChina Clinical Trails Registry (ChiCTR2400086931); registered July 15, 2024. https://www.chictr.org.cn/ .
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