Inhibition of Proteus mirabilis growth through gallium-based disruption of iron and heme metabolism.

Devendra Kumar, Jack G Hirz, Seoung-Ryoung Choi, John S Stevenson, Prabagaran Narayanasamy, Bradley E Britigan, Jason E Michaud

Abstract read

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In one paragraph

Article in The Journal of antibiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devendra KumarDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.

Jack G HirzDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.

Seoung-Ryoung ChoiDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.

John S StevensonDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.

Prabagaran NarayanasamyDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Bradley E BritiganDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Jason E MichaudDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE, USA. jmichaud@unmc.edu.ORCID http://orcid.org/0000-0001-7463-2156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased incidence of multi-drug resistant (MDR) Proteus mirabilis highlights the need for novel antibiotics targeting P. mirabilis. In this study, we examined the potential antibacterial effects of gallium-based antimicrobials on P. mirabilis. We performed in vitro susceptibility testing of gallium compounds against P. mirabilis UTI isolates. Ga(NO

Indexed as

Anti-Bacterial AgentsGalliumHemeIronProteus mirabilisProtoporphyrinsAnimalsMicrobial Sensitivity TestsProteus InfectionsUrinary Tract InfectionsAnti-Bacterial AgentsGalliumgallium nitrateHemeIronprotoporphyrin IXProtoporphyrins

Identifiers

PMID42337371

DOI10.1038/s41429-026-00941-z

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.