Evidence map›Paper›PMID 42337282›Full record

Trial reportScientific reports2026

In vivo exposure to cranberry juice suppresses dental plaque regrowth and acid production in adults and children: a PGRM study.

Christine D Wu, Wei Li, Monique Luu, Evelina Kratunova, Qian Xie

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christine D WuDepartment of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, USA. chriswu@uic.edu.
Wei LiDepartment of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, USA.
Monique LuuDepartment of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, USA.
Evelina KratunovaDepartment of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, USA.
Qian XieDepartment of Endodontics, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The American cranberry, Vaccinium macrocarpon, has been reported to benefit human health and is a popular remedy for self-treatment of urinary tract infections. Cranberry proanthocyanidins have been shown to inhibit growth and biofilm formation of oral pathogens and dental plaque bacteria associated with dental caries and periodontal disease. To evaluate the hypothesis that short term in vivo exposure to cranberry juice inhibits metabolic activity of human dental plaque bacteria the Plaque Glycolysis and Regrowth method (PGRM) was used. Two independent randomized crossover trials were conducted: one in adults (18-64 years, N = 8) and one in children (7-12 years, N = 14). Commercially marketed Ocean Spray

Indexed as

AcidsDental PlaqueFruit and Vegetable JuicesVaccinium macrocarponAdolescentAdultChildCross-Over StudiesFemaleHumansMaleMiddle AgedYoung AdultAcids

Identifiers

PMID42337282
PMCPMC13574803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.