ArticleInternational ophthalmology2026
Improvement of pattern electroretinogram parameters following glaucoma surgery.
Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo assess the dynamics of Pattern Electroretinogram (PERG) parameters following glaucoma surgery in individuals with glaucomatous optic neuropathy.
methodsThe is a single center retrospective study. Preoperative PERG were conducted on moderate and advanced glaucoma patients scheduled for glaucoma surgery. Subsequently, the patients underwent an additional PERG a few months after the procedure. Comparative analysis focused on the PERG parameters (Mag, MagD and MagD/Mag ratio) before and after the glaucoma surgery in eyes achieving successful intraocular pressure (IOP) reduction post-operatively.
resultsThe study enrolled 23 eyes from 21 consecutive patients who underwent successful glaucoma surgery between January 2021 and December 2023, each with both pre and post-operative PERG assessments. Postoperatively, there was a significant improvement of all the PERG parameters (0.97 ± 0.29 to 1.36 ± 0.29 μV, 0.55 ± 0.3 to 0.84 ± 0.42 μV, 0.52 ± 0.2 to 0.68 ± 0.25 for Mag, MagD and MagD/Mag ratio respectively, all p < 0.05). Three patients who had no IOP reduction postoperatively showed no improvement of all PERG parameters following the surgery.
conclusionsGlaucoma surgery, leading to effective IOP reduction, may demonstrate a positive impact on the functional activity of the retinal ganglion cells, as evidenced by the enhancement in PERG parameters post-operatively.
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