Evidence map›Paper›PMID 42336964›Full record

ArticleScientific reports2026

pH-responsive delivery of hydrophobic anticancer drugs using boron and nitrogen Co-doped carbon dots as fluorescent nanocarriers.

Seyed Mostafa Jafari, Saeed Masoum, Elahe Seyed Hosseini

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seyed Mostafa JafariDepartment of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
Saeed MasoumDepartment of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran. masoum@kashanu.ac.ir.ORCID 0000-0002-8504-1340
Elahe Seyed HosseiniAnatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. Elaheir.1987@gmail.com.

Funding

University of Kashan 1311478/3
6 · The paper itself

Abstract

In recent years, carbon dots have attracted considerable attention within the nanocarbon family due to their remarkable advantages and interesting properties such as high solubility, biocompatibility, tunable photoluminescence, and so on. Carbon dots can also be designed and synthesized according to the desired functionalities (such as sensors, biosensors, or drug delivery systems). In the present study, nitrogen- and boron-co-doped carbon dots (abbreviated as "NBCDs") were successfully used as highly fluorescent and efficient nanocarriers to load two hydrophobic anticancer drugs, namely curcumin (CUR) and paclitaxel (PTX). The NBCDs were characterized before and after conjugation with CUR and PTX using spectroscopic techniques. After calculating the drug loading capacity (LC%) and adsorption efficiency (AE%) of the NBCDs nanocarriers, the drug release behavior was evaluated in two buffer media (pH 5.0 and pH 7.4) using the dialysis bag method for 72 h. Finally, the pH-dependent release behavior of the drugs was analyzed using several kinetic models.

Indexed as

Antineoplastic AgentsBoronCarbon Quantum DotsDrug CarriersDrug Delivery SystemsNitrogenCarbonCurcuminDrug LiberationHydrogen-Ion ConcentrationHydrophobic and Hydrophilic InteractionsPaclitaxelAntineoplastic AgentsBoronCarbonCurcuminDrug CarriersNitrogenPaclitaxelAnticancer drugCarbon dotsCurcuminDrug release modelsNanocarrierPaclitaxel

Identifiers

PMID42336964
PMCPMC13575120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.