Evidence map›Paper›PMID 42336843›Full record

ArticleNature communications2026

Reasoning in machine vision by learning fast and slow thinking.

Shaheer U Saeed, Yipei Wang, Veeru Kasivisvanathan, Brian R Davidson, Matthew J Clarkson, Yipeng Hu, Daniel C Alexander

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaheer U SaeedCentre for Bioengineering, Queen Mary University of London, London, UK. shaheer.saeed@qmul.ac.uk.ORCID http://orcid.org/0000-0002-5004-0663
Yipei WangUCL Hawkes Institute, University College London, London, UK.
Veeru KasivisvanathanCentre for Urology Imaging, Prostate, AI and Surgical Studies (COMPASS) Research Group, Division of Surgery and Interventional Science, University College London, London, UK.
Brian R DavidsonDivision of Surgery and Interventional Science, University College London, London, UK.
Matthew J ClarksonUCL Hawkes Institute, University College London, London, UK.ORCID http://orcid.org/0000-0002-5565-1252
Yipeng HuUCL Hawkes Institute, University College London, London, UK.ORCID http://orcid.org/0000-0003-4902-0486
Daniel C AlexanderUCL Hawkes Institute, University College London, London, UK.ORCID http://orcid.org/0000-0003-2439-350X

Funding

Cancer Research UK (CRUK) C73666/A31378Cancer Research UK (CRUK) EDDAPA-2024/100014DH | National Institute for Health Research (NIHR) University College London Hospitals Biomedical Research CentreRCUK | Engineering and Physical Sciences Research Council (EPSRC) P/T029404/1
6 · The paper itself

Abstract

Reasoning is a hallmark of human intelligence, enabling adaptive decision-making in complex unfamiliar scenarios. In contrast, machine intelligence remains bound to training data, unable to dynamically refine solutions at inference. While recent advances have explored machine reasoning - trading inference-time compute for improved performance - they focus on verbal domains such as mathematical problem-solving where explicit rules govern step-by-step solution generation. Many tasks lack sufficient labelled data and require alternative performance improvement mechanisms, such as inference-time compute. Here we present a paradigm for machine reasoning in vision, enabling performance improvements with increasing thinking time (inference-time compute), even with limited labelled data. Our approach is inspired by dual-process theories of human cognition, integrating a fast-thinking System I module for generating and verifying solutions in familiar tasks, with a slow-thinking System II module that iteratively refines predictions using self-play reinforcement learning, even when task-specific data is limited. This paradigm involves proposing, competing over, and refining solutions until convergence. We demonstrate that extended inference-time compute yields superior performance compared to large-scale supervised learning, foundation models, and human experts in vision tasks. These include computer-vision benchmarks and cancer localisation across five organs, highlighting the potential of inference-time compute for data-scarce problems.

Indexed as

Artificial IntelligenceMachine LearningThinkingCognitionDecision MakingHumansLearningProblem SolvingReinforcement Machine LearningSoft Computing

Identifiers

PMID42336843
PMCPMC13443672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.