ArticleBMJ open2026
Assessing the impact of combined nutritional and physical activity interventions for patients with atrial fibrillation who are overweight: a systematic review protocol.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with reduced quality of life and increased healthcare utilisation. AF is increasingly recognised as a manifestation of an underlying cardiometabolic disease process, with obesity and related metabolic risk factors contributing to its development and progression. Consequently, upstream risk factor modification, including structured weight management, has emerged as a potential strategy to improve AF outcomes. While dietary and exercise interventions have been studied individually, the effectiveness of programmes combining both components has not been systematically reviewed in patients with AF who are overweight or obese. This review aims to assess the impact of combined nutritional and physical activity interventions on AF-related outcomes. METHODS AND ANALYSIS: A systematic search will be conducted in MEDLINE, CINAHL, EMBASE and EMCARE from database inception to April 2026. Eligible studies will include randomised controlled trials, quasi-experimental studies and controlled cohort studies evaluating combined dietary and physical activity interventions in adults with AF who are overweight or obese. The primary outcome will be AF symptom burden measured using validated instruments. Secondary outcomes will include quality of life, anthropometric measures, metabolic parameters and AF arrhythmia burden. Risk of bias will be assessed using RoB 2 and Risk of Bias in Non-randomised Studies of Interventions. Where appropriate, meta-analysis will be performed using random-effects models. ETHICS AND DISSEMINATION: Ethical approval is not required. Findings will be disseminated through peer-reviewed publications and scientific meetings. PROSPERO REGISTRATION NUMBER: Open Science Framework (OSF; https://doi.org/10.17605/OSF.IO/HCUZ3).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.