Evidence map›Paper›PMID 42336469›Full record

ArticleRenal failure2026

Spatiotemporal dynamics of renal distal convoluted tubule dilatation and cyst formation in nephronophthisis type 1 mice.

Weina Zhang, Guanghua Xu, Xinyu Su, Jiayong Lai, Zhihe Xue, Tian Li, Hongbo Huang, Ruxin Li, Liangzhong Sun, Yanbing Li

Abstract read
In one paragraph

Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weina ZhangDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0009-0000-7139-9678
Guanghua XuNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.ORCID 0000-0001-9703-8686
Xinyu SuDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jiayong LaiDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhihe XueDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Tian LiNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Hongbo HuangNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Ruxin LiNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Liangzhong SunDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0003-1962-8626
Yanbing LiNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephronophthisis (NPH), a rare but serious ciliopathy, is the predominant genetic cause of end-stage kidney disease (ESKD) in children and adolescents. Renal tubular dilatation and cyst formation are key pathological features of NPH. The mechanisms underlying renal cystogenesis remain poorly understood. This study employed sex-balanced

Indexed as

Kidney Diseases, CysticKidney Tubules, DistalAdaptor Proteins, Signal TransducingAnimalsCytoskeletal ProteinsDilatation, PathologicDisease Models, AnimalFemaleHumansMaleMiceMice, KnockoutAdaptor Proteins, Signal TransducingCytoskeletal ProteinsNphp1 protein, mouseNephronophthisisNPHP1pathological anatomyrenal cystspatiotemporal dynamic

Identifiers

PMID42336469
PMCPMC13292302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.