Evidence map›Paper›PMID 42336106›Full record

ArticleDiabetes research and clinical practice2026

Reproducibility of the diagnosis of diabetes by the 1-hour oral glucose tolerance test is substantial.

Anne E Sumner, Anika J Shah, Ananya Bharadwaj, Grace G Smith, Kauthrah Ntabadde, Bella S Izere, Christopher W DuBose, Ram Jagannathan, David B Sacks

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes research and clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anne E SumnerSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States; Hypertension in Africa Research Team, North-West University, Potchefstroom, North-West, South Africa; National Institute of Minority Health and Health Disparities, Bethesda, MD, United States. Electronic address: anne.sumner@nih.gov.
Anika J ShahSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Ananya BharadwajSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Grace G SmithSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Kauthrah NtabaddeSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Bella S IzereSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Christopher W DuBoseSection on Diabetes, Nutrition and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Ram JagannathanSchool of Public Health, Emory University, Atlanta, Georgia.
David B SacksClinical Center, National Institutes of Health, Bethesda, MD, United States.

Funding

Heart Disease Risk Factors In African AmericansZIADK047023 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI SUMNER, ANNE · 2009 to 2025
$16.3M
Intramural NIH HHS ZIA DK047023
6 · The paper itself

Abstract

Diagnostic reproducibility of diabetes was substantial (ҝ-statistic = 0.74, 95%CI: 0.58-0.90) in 154 African descent individuals with 1 h-OGTTs performed 10 ± 7d (mean ± SD) apart. Diabetes was diagnosed in 34 individuals with 65%(22/34) detected at both visits (non-switchers) and 35%(12/34) at one visit (switchers). With insulin resistance greater in non-switchers, 1 h-OGTT reproducibility may be better if insulin resistance present.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2AdultBlood GlucoseFemaleGlucose Tolerance TestHumansInsulin ResistanceMaleMiddle AgedReproducibility of ResultsBlood Glucose1 h-OGTTBeta-cell insufficiencyInsulin resistance

Identifiers

PMID42336106
PMCPMC13410393

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.