Evidence map›Paper›PMID 42335445›Full record

ArticleNeurology(R) neuroimmunology & neuroinflammation2026

Immunity Gone Viral: Subacute Cognitive Decline With Multifocal Brain Lesions in Neuromyelitis Optica Spectrum Disorder.

Sonali Ajwani, Brian G Weinshenker, Caterina Giannini, Thomas M Habermann, Yucai Wang, Pamela Skrabek, Abedallah Balusha, Michel Toledano, Susan E Horsman, Claudia Francesca Lucchinetti and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology(R) neuroimmunology & neuroinflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sonali AjwaniDell Medical School, University of Texas at Austin, TX.ORCID 0009-0007-3301-1397
Brian G WeinshenkerDepartment of Neurology, Mayo Clinic, Rochester, MN.ORCID 0000-0001-5806-6203
Caterina GianniniDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.ORCID 0000-0003-2757-6782
Thomas M HabermannDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN.ORCID 0000-0003-3532-9132
Yucai WangDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN.
Pamela SkrabekDepartment of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0009-0002-2686-175X
Abedallah BalushaDepartment of Internal Medicine, Section on Neurology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Michel ToledanoDepartment of Neurology, Mayo Clinic, Rochester, MN.ORCID 0000-0002-9046-7880
Susan E HorsmanDepartment of Pharmacy, Mayo Clinic, Rochester, MN; and.ORCID 0000-0002-4572-9730
Claudia Francesca LucchinettiDell Medical School, University of Texas at Austin, TX.ORCID 0000-0001-5070-1196
Eoin P FlanaganDepartment of Neurology, Mayo Clinic, Rochester, MN.ORCID 0000-0002-6661-2910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subacute cognitive decline and imbalance in aquaporin-4-antibody-seropositive neuromyelitis optica spectrum disorder (AQP4+NMOSD) treated with mycophenolate has a broad differential diagnosis, including cerebral involvement of AQP4+NMOSD, infections, or other complications of immunosuppression. In this article, we highlight the diagnostic and treatment approach in a patient with AQP4+NMOSD who developed multifocal brain lesions.

Indexed as

BrainCognitive DysfunctionNeuromyelitis OpticaAquaporin 4HumansAquaporin 4

Identifiers

PMID42335445
PMCPMC13308546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.