Evidence map›Paper›PMID 42335277›Full record

ArticleMilitary medicine2026

Risk of First Adjustment Disorder in U.S. Army Soldiers.

Holly B Herberman Mash, James A Naifeh, Rachel Shor, Pablo A Aliaga, Carol S Fullerton, Tzu-Cheg Kao, Nancy A Sampson, Ronald C Kessler, David M Benedek, Murray B Stein and 1 more

Abstract read
In one paragraph

Article in Military medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Holly B Herberman MashDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.ORCID 0000-0001-5562-6009
James A NaifehDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Rachel ShorDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Pablo A AliagaDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Carol S FullertonDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Tzu-Cheg KaoDepartment of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA 02115, United States.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA 02115, United States.
David M BenedekDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Murray B SteinDepartment of Psychiatry, University of California San Diego, La Jolla, CA 92093, United States.
Robert J UrsanoDepartment of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.

Funding

Modifiable Risk and Protective Factors for Suicidal Behaviors in the US ArmyU01MH087981 · NIMH · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI STEIN, MURRAY B., URSANO, ROBERT J. · 2009 to 2013
$65.0M
Army STARRS (2009-2015)Department of the Army and the National Institute of Mental Health (NIMH) U01MH087981Department of the Army, the Department of WarDepartment of War under USUHS HU0001-2520033NIMH NIH HHS U01 MH087981STARRS-LSthe Department of Veteran Affairsthe National Institute of Mental HealthUnited States government
6 · The paper itself

Abstract

introductionAdjustment disorder is the most common mental health diagnosis in the U.S. military and one of the most common globally, yet its patterns and predictors are rarely studied. Identifying career phases and characteristics associated with increased risk of first adjustment disorder (AD) diagnosis among U.S. Army soldiers can inform targeted prevention and intervention efforts. MATERIALS AND

methodsThis longitudinal, retrospective cohort study analyzed data from the Study to Assess Risk and Resilience in Servicemembers-Longitudinal Study (STARRS-LS). Administrative medical and personnel records from active duty Regular Army enlisted soldiers (2015-19) were used to identify all 118,735 person-months with a first AD diagnosis and a representative, stratified probability sample of control person-months with no history of AD diagnosis (n = 316,275). Risk of first AD diagnosis was estimated as function of time in service, stratified by sex and occupation. Logistic regression examined socio-demographic, service-related, and mental health risk factors for first AD diagnosis during periods of greatest risk. This study was approved by the Institutional Review Boards of STARRS-LS collaborating institutions.

resultsAD cases were 77.2% male, 54.9% ≤24 years old, and 51.0% White Non-Hispanic. For 63.7% of cases, AD was their first documented mental disorder during service. Of those, 25.5% had been diagnosed with a stressor or marital problem in the previous 12 months. Risk of first AD by time in service was bimodal, with elevated risk during the first 1-4 years ("early-career") and years 17-20 ("late-career"). This pattern was consistent across sex and occupational groups. Based on a sample size-adjusted alpha level, 12 of 13 multivariable risk factors were associated with early-career AD, whereas 7 of 13 were associated with late-career AD. Notable risk factors among early- and late-career soldiers were female sex (early-career: OR = 2.0; 95% CI = 1.9-2.0; late-career: OR = 1.4; 95% CI = 1.3-1.5), deployment status (early: never-deployed, OR = 2.0; 95% CI = 1.9-2.2, previously-deployed, OR = 1.6; 95% CI = 1.4-1.8; late: previously-deployed, OR = 1.7; 95% CI = 1.5-2.0), and recency of previous mental health diagnosis (early: past-month, OR = 3.7; 95% CI = 3.6-3.8; late: past-month, OR = 4.2; 95% CI = 3.9-4.5), stressor/marital problems (early: past-month, OR = 5.7; 95% CI = 5.5-5.8; late: past-month, OR = 4.1; 95% CI = 3.8-4.6), and postconcussive syndrome (early: past-month, OR = 3.0; 95% CI = 2.6-3.5; late: past 2-3-months, OR = 2.7; 95% CI = 1.5-4.8). Magnitudes of other significant ORs were more modest. Interactions indicated that associations of 9 risk factors differed for early versus late career soldiers.

conclusionsFirst AD risk is highest among soldiers either beginning their Army careers or approaching retirement eligibility. Differences in risk factors across groups highlight the importance of considering distinct military and life experiences/stressors when attempting to target and tailor interventions for those at risk of AD.

Identifiers

PMID42335277
PMCPMC13353912

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