Trial reportThe American journal of managed care2026
Cost of behavioral messaging interventions for cardiovascular medication adherence.
Trial report in The American journal of managed care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03973931 (Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications (The Nudge Study)
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivesMobile health (mHealth) interventions have promise as low-cost tools promoting behavioral change. We evaluated the implementation and maintenance costs of 3 text messaging strategies aimed at improving cardiovascular medication adherence. STUDY
designThe Nudge Study (NCT03973931) was a randomized pragmatic trial that evaluated prescription refill adherence across 3 health systems. We estimated costs over the 4-year study period.
methodsAfter adjusting for inflation to 2023 US$, we calculated net non-research-related labor and materials costs in total and by The Nudge Study arm, assigning usual care a $0 cost. We calculated incremental cost-effectiveness ratios (ICERs) using observed cost; payoffs of the median reduction in number of gap days without medications; and the study's published rates of death, hospitalization, and emergency visits.
resultsProgram start-up costs were similar across the 3 health care systems (mean [SD], $2954 [$352]). Across the 53 months of the study and comprising start-up, implementation, and program delivery phases, the mean monthly cost to deliver all messaging strategies was $3949 and 1430 unique patients on average received any type of message monthly, resulting in an estimated cost of $2.76 per patient per month. ICER values were low, and there were no significant differences across treatment strategy or outcome.
conclusionsProviding medication adherence support via mobile messaging may be a low-cost solution for some hospital systems.
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Registered trials
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