SynthesisCancer2026
Fertility preservation access among female adolescents and young adults with cancer: A systematic review.
Synthesis in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fertility preservation access among female adolescents and young adults with cancer: A systematic review.Cancer · 2026Pooled it
- Bridging pediatric and adult neuro-oncology: Insights into adolescents and young adults (AYA) central nervous system tumors.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Global burden and trends of tracheal, bronchus, and lung cancer in adolescents and young adults: a secondary analysis of the Global Burden of Disease Study 2021.Journal of thoracic disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Adolescents and young adults (AYAs; aged 15-39 years) with cancer face significant threats to future fertility. Despite fertility preservation (FP) guidelines, disparities in access persist, particularly among female AYAs. This systematic review aims to describe FP access and explore disparities by sociodemographic and clinical factors among female AYAs with cancer in the United States. This systematic review was registered in PROSPERO (CRD420251077846) and conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, the Cumulative Index to Nursing and Allied Health Literature, and Embase were searched from May 1, 2006, through July 17, 2025. Eligible studies were US-based, peer-reviewed observational or interventional studies examining FP access among female AYAs with cancer. Two reviewers independently screened articles, extracted data, and appraised methodological quality with Joanna Briggs Institute tools. Among 10,151 records, 25 studies met the inclusion criteria. All included studies demonstrated high methodological quality and low risk of bias. Reported rates of FP discussions ranged from 9% to 75%, referrals or consultations with fertility specialists ranged from 0.9% to 57%, and completion of FP procedures ranged from 0.56% to 70.3%. Facilitators of access included younger age, private insurance, nulliparity, higher socioeconomic status, certain cancer types, and more recent diagnosis year. Barriers included non-Hispanic Black or Hispanic race/ethnicity, lower income, public insurance, and residence in rural or low-resource areas. Institutional interventions improved access but did not eliminate the underlying disparities. Substantial inequities in FP access persist for female AYAs with cancer in the United States, which underscores the need for routine integration of FP into oncology care and for interventions that address structural and geographic barriers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.