Evidence map›Paper›PMID 42334783›Full record

ArticleEndocrine2026

Ultrasound-guided thermal ablation for papillary thyroid microcarcinoma with calcifications: short-term imaging outcomes.

Xinyi Zhou, Fan Yang, Lei Zhang, Bolin Wu, Zhao Liu, Yue Li, Xitian Liang, Yuanjuan Hu, Maoxiang Zhang, Wen Cheng and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinyi ZhouDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Fan YangDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Lei ZhangDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Bolin WuDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Zhao LiuDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Yue LiDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Xitian LiangDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Yuanjuan HuDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China.
Maoxiang ZhangInstitute of Cancer Prevention and Treatment, Harbin Medical University, 150081, Harbin , China.
Wen ChengDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China. hrbchengwen@163.com.
Qiucheng WangDepartment of ultrasound, Harbin medical university cancer hospital, No. 150, Haping Road, Nangang District, Harbin, 150081, Heilongjiang Province, China. haerbincss@126.com.

Funding

the National Natural Science Foundation of China No. 82402278
6 · The paper itself

Abstract

objectiveTo evaluate the technical feasibility and short-term imaging evolution of ultrasound-guided thermal ablation for papillary thyroid microcarcinoma (PTMC) with calcification, while also analyzing the differences associated with calcification sizes.

methodsA total of 69 PTMCs with calcification were identified from 69 patients who underwent RFA or MWA between January 2022 and April 2025, and were retrospectively analyzed. The following outcomes were evaluated: technical success, changes in tumor volume and volume reduction rate (VRR), complete tumor disappearance, and complications.

resultsThe technical success rate was 100%. During a median follow-up of 15 months (range 6-33 months), significant differences in mean volume and VRR (versus baseline) were observed at all follow-up time points but not at the 3-month point. The overall complete disappearance rate was 43.5% (median 25 months), significantly higher and faster in the microcalcification group (55.3%; median 25 months) than that in the macrocalcification group (29.0%; median 30 months) (P = 0.029). The rate of overall complications was 2.9%, with no significant intergroup difference (2.6% vs. 3.3%, P = 1.000).

conclusionsUltrasound-guided thermal ablation for PTMC with calcification is technically feasible. On short-term sonographic assessment, although favorable changes were observed, the macrocalcification group showed a lower complete disappearance rate and a longer median time to disappearance.

Indexed as

CalcinosisCarcinoma, PapillaryRadiofrequency AblationThyroid NeoplasmsUltrasonography, InterventionalAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeCalcificationMacrocalcificationsMicrocalcificationsPapillary thyroid microcarcinomaThermal ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.