Evidence map›Paper›PMID 42334674›Full record

ArticleJournal of neurovirology2026

Zika virus infection in the brains of lymphocyte-deficient mice does not lead to neurological symptoms despite sustained high viral load.

Amelia Montemarano, Elizabeth Balint, Ali A Ashkar

Abstract read
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Article in Journal of neurovirology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amelia Montemarano *Department of Medicine, McMaster Immunology Research Center, McMaster University, 1280 Main St. West, MDCL 4074, Hamilton, ON, L8N 3Z5, Canada.
Elizabeth Balint *Department of Medicine, McMaster Immunology Research Center, McMaster University, 1280 Main St. West, MDCL 4074, Hamilton, ON, L8N 3Z5, Canada.
Ali A AshkarDepartment of Medicine, McMaster Immunology Research Center, McMaster University, 1280 Main St. West, MDCL 4074, Hamilton, ON, L8N 3Z5, Canada. ashkara@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) infections have been linked to severe neurological disorders, including microcephaly and Guillain-Barré syndrome in humans as well as mouse models of ZIKV infection. Despite the association, the mechanisms underlying ZIKV-induced neuropathology remain incompletely understood. We have recently shown that antigen independent CD8

Indexed as

BrainZika VirusZika Virus InfectionAnimalsCD8-Positive T-LymphocytesDisease Models, AnimalLymphocytesMiceMice, KnockoutMyeloid CellsReceptor, Interferon alpha-betaViral LoadIfnar1 protein, mouseReceptor, Interferon alpha-betaMicrogliaMonocytesNeurological diseaseNeurotropic infectionsZika virus

Identifiers

PMID42334674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.