Evidence map›Paper›PMID 42334585›Full record

ReviewChirurgie (Heidelberg, Germany)2026

[Massive/mass-forming ductular reaction (MDR) in angioinvasive hepatocellular carcinoma : Pathogenesis and differential diagnoses of a hepatic pseudotumor].

Anne Kristin Fischer, Reinhard Büttner, Thorsten Persigehl, Hans-Peter Fischer

Abstract readEnglish AbstractReview
In one paragraph

Review in Chirurgie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne Kristin FischerInstitut für Pathologie, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland. anne.fischer1@uk-koeln.de.
Reinhard BüttnerInstitut für Pathologie, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Thorsten PersigehlInstitut für Diagnostische und Interventionelle Radiologie, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Hans-Peter FischerInstitut für Pathologie, Universitätsklinik Bonn, Venusberg Campus 1, 53127, Bonn, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Massive/mass-forming ductular reaction (MDR) of the liver is a form of extensive parenchymatous remodelling under conditions of focal relative ischemia. This pseudotumoral reaction of the liver parenchyma is induced by locally extended occlusion of hepatic venous, portal venous and sinusoidal blood vessels. It is often caused by an angioinvasive obliteration from a coincidental malignant tumor but an occurrence in a benign context in a liver cirrhosis or after extensive liver necrosis is possible. The certain preinterventional classification is not always possible so that a differentiation with a liver biopsy is necessary.

Indexed as

Carcinoma, HepatocellularLiverLiver DiseasesLiver NeoplasmsBiopsyDiagnosis, DifferentialHumansNeoplasm InvasivenessCholangiocarcinomaDifferentiation by liver biopsyLiver remodelling processObstruction of the hepatic circulationPseudotumoral hepatic lesion

Identifiers

PMID42334585
PMCPMC13601105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.