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ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Impact of application repetition on Joule heating and lesion formation using a circular-shaped pulsed field catheter.

Mizuki Okumura, Shintaro Yamagami, Masaya Akiyama, Yuta Nakano, Yu Amano, Toyoki Okuda, Tsukasa Motoyoshi, Ryuki Chatani, Hirokazu Kondo, Toshihiro Tamura

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Mizuki OkumuraDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Shintaro YamagamiDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan. milky323@kuhp.kyoto-u.ac.jp.
Masaya AkiyamaDepartment of Clinical Engineering, Tenri Hospital, Tenri, Nara, Japan.
Yuta NakanoDepartment of Clinical Engineering, Tenri Hospital, Tenri, Nara, Japan.
Yu AmanoDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Toyoki OkudaDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Tsukasa MotoyoshiDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Ryuki ChataniDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Hirokazu KondoDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Toshihiro TamuraDepartment of Cardiology, Tenri Hospital, Tenri, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPulsed field ablation (PFA) is a non-thermal ablation modality, but repeated high-voltage applications can still cause Joule heating at the electrode-tissue interface. We evaluated the effects of application repetition and inter-application intervals on temperature rise and lesion depth using a circular-shaped PFA catheter. METHODS AND

resultsIn an in vitro potato model, a circular-shaped PFA catheter was tested under five settings: 1×, 2×, 2× with a 10-s interval, 4×, and 4× with a 10-s interval. Maximum electrode surface temperature was measured using a thermal camera, and lesion depth was assessed by TTC staining (n = 5 per setting). Temperature increased significantly with application repetition and was attenuated by a 10-s interval (overall P < 0.0001). Lesion depth also increased with repetition (overall P < 0.0001), but did not differ significantly between interval and no-interval conditions at equal application numbers.

conclusionIn this simplified in vitro model, a short inter-application interval was associated with attenuation of temperature rise during repeated PFA delivery, while lesion depth was not significantly reduced.

Indexed as

Atrial fibrillationCatheter ablationElectrode temperatureLesion depth

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.