Evidence map›Paper›PMID 42334525›Full record

ArticleMolecular and cellular biochemistry2026

Synthesis and multilevel evaluation of benzimidazole-based anticancer compounds: DNA/serum albumin interaction, and in-depth theoretical insights.

Sevgi Kundu, Senem Akkoc, Yalçın Erzurumlu, Sadeq K Alhag, Lamya Ahmed Alkeridis, Mehran Feizi-Dehnayebi

Abstract read
In one paragraph

Article in Molecular and cellular biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sevgi KunduInstitute of Health Sciences, Department of Basic Pharmaceutical Sciences, Suleyman Demirel University, Isparta, 32260, Türkiye, Turkey.ORCID http://orcid.org/0009-0008-0121-0882
Senem AkkocFaculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Suleyman Demirel University, Isparta, 32260, Türkiye, Turkey. senemakkoc@sdu.edu.tr.ORCID http://orcid.org/0000-0002-1260-9425
Yalçın ErzurumluFaculty of Pharmacy, Department of Biochemistry, Suleyman Demirel University, 32260, Isparta, Turkey.ORCID http://orcid.org/0000-0001-6835-4436
Sadeq K AlhagHealth Specialties, Basic Sciences and Applications Unit, King Khalid University, Applied College, Mohayil Asir Abha, 61421, Saudi Arabia.ORCID http://orcid.org/0000-0001-6695-6492
Lamya Ahmed AlkeridisDepartment of Biology, Collage of Science, Princess Nourah bint Abdulrahman University, P.O.Box 84428, Riyadh, 11671, Saudi Arabia.ORCID http://orcid.org/0000-0001-6661-3625
Mehran Feizi-DehnayebiFaculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Suleyman Demirel University, Isparta, 32260, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-7868-9085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the scope of this investigation, two novel compounds (3a and 3b) were designed and synthesized in two steps. Compounds 3a and 3b were tested utilizing the MTT study to evaluate their in vitro cytotoxic activity against healthy human embryonic kidney, lung cancer, breast cancer, and human liver cancer cell lines. It was determined that compound 3b exhibited high levels of cytotoxic activity against both liver and breast cancer cell lines, with IC

Indexed as

Antineoplastic AgentsBenzimidazolesDNASerum AlbuminApoptosisHumansMCF-7 CellsMolecular Docking SimulationOxidative StressAntineoplastic AgentsbenzimidazoleBenzimidazolesDNASerum AlbuminApoptosisBenzimidazoleCancerCytotoxic activityDNA/BSAOxidative stressTheoretical studies

Identifiers

PMID42334525
PMCPMC13524987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.