Evidence map›Paper›PMID 42333769›Full record

ArticleJournal of biochemical and molecular toxicology2026

Synthesis, Characterization, Antioxidant Evaluation, Cytotoxicity Studies, and Molecular Docking of Novel Sulfonamide Derivatives.

Ouissal Bouraoui, Güldeniz Şekerci, Khaled Mesbah, James A Ezugwu, Rachid Benkiniouar, Suat Tekin, Fatümetüzzehra Küçükbay, Houssem Boulebd, Hasan Küçükbay

Abstract read
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In one paragraph

Article in Journal of biochemical and molecular toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ouissal BouraouiLaboratory of Natural Products of Plant Origin and Organic Synthesis, Frères Mentouri University Constantine 1, Constantine, Algeria.
Güldeniz ŞekerciDepartment of Physiology, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-0811-4454
Khaled MesbahLaboratory of Natural Products of Plant Origin and Organic Synthesis, Frères Mentouri University Constantine 1, Constantine, Algeria.
James A EzugwuDepartment of Chemistry, Faculty of Arts and Sciences, İnonu University, Malatya, Turkey.ORCID https://orcid.org/0000-0001-6607-6954
Rachid BenkiniouarLaboratory of Natural Products of Plant Origin and Organic Synthesis, Frères Mentouri University Constantine 1, Constantine, Algeria.
Suat TekinDepartment of Physiology, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-2757-1802
Fatümetüzzehra KüçükbayDepartment of Basic Pharmaceutical Sciences, İnonu University, Faculty of Pharmacy, Malatya, Turkey.
Houssem BoulebdLaboratory of Synthesis of Molecules with Biological Interest, Department of Chemistry, Faculty of Exact Sciences, University Frères Mentouri Constantine 1, Constantine, Algeria.ORCID https://orcid.org/0000-0002-7727-8583
Hasan KüçükbayDepartment of Chemistry, Faculty of Arts and Sciences, İnonu University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-7180-9486

Funding

TUBİTAK (The Scientific and Technological Research Council of Turkey) E-21514107-115.02-612434/2221 Program 2024/1
6 · The paper itself

Abstract

A series of novel sulfonamide derivatives (4a-i) was synthesized via a three-step sequence involving Schiff base formation, sodium borohydride reduction to the corresponding secondary amines (2a-i), and subsequent treatment with p-toluenesulfonyl chloride in the presence of sodium carbonate. The structures of all intermediates and final products were unambiguously confirmed by FT-IR,

Indexed as

Antineoplastic AgentsAntioxidantsMolecular Docking SimulationSulfonamidesCell Line, TumorHumansStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsSulfonamidesA2780antioxidant activitycytotoxicityDPPH assayLNCaPmolecular dockingMTT assaySchiff basesulfonamide derivatives

Identifiers

PMID42333769
PMCPMC13288007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.