Evidence map›Paper›PMID 42333700›Full record

ArticleJournal of the American Heart Association2026

Neighborhood-Level Racial and Ethnic Residential Segregation and Incidence of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.

Utibe R Essien, Katharine Harrington, Shaina J Alexandria, Philip Greenland, Susan R Heckbert, Moyses Szklo, Mahasin S Mujahid, Mercedes R Carnethon, Karol E Watson, Jasmyn J Tang and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Utibe R EssienDivision of General Internal Medicine and Health Services David Geffen School of Medicine at the University of California Los Angeles Los Angeles CA USA.ORCID 0000-0002-4494-5028
Katharine HarringtonDepartment of Preventive Medicine Feinberg School of Medicine at Northwestern University Chicago IL USA.ORCID 0000-0002-2829-5133
Shaina J AlexandriaDepartment of Preventive Medicine Feinberg School of Medicine at Northwestern University Chicago IL USA.ORCID 0000-0002-3069-4299
Philip GreenlandDepartment of Preventive Medicine Feinberg School of Medicine at Northwestern University Chicago IL USA.ORCID 0000-0002-6327-2439
Susan R HeckbertDepartment of Epidemiology School of Public Health at the University of Washington Seattle WA USA.ORCID 0000-0002-7100-512X
Moyses SzkloDivision of Cardiovascular and Clinical Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0001-9433-6266
Mahasin S MujahidDivision of Epidemiology School of Public Health at the University of California Berkeley Berkeley CA USA.ORCID 0000-0001-9795-9338
Mercedes R CarnethonDepartment of Preventive Medicine Feinberg School of Medicine at Northwestern University Chicago IL USA.ORCID 0000-0001-7035-0848
Karol E WatsonDivision of Cardiology David Geffen School of Medicine at University of California Los Angeles Los Angeles CA USA.ORCID 0000-0003-3658-6165
Jasmyn J TangDivision of General Internal Medicine and Health Services David Geffen School of Medicine at the University of California Los Angeles Los Angeles CA USA.ORCID 0009-0001-8737-0447
Kiarri N KershawDepartment of Preventive Medicine Feinberg School of Medicine at Northwestern University Chicago IL USA.ORCID 0000-0002-0063-6397

Funding

Task Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1M
TO EXERCISE OPTION PERIOD ONE (1) FOR TASK AREA A - MESA CORE OPERATIONS, FIELD CENTER.75N92020D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI SIEGEL, JONATHAN H · 2020 to 2025
$4.5M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI PANKOW, JAMES S · 2020 to 2025
$4.4M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00003 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POST, WENDY S · 2020 to 2025
$3.8M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00007 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BERTONI, ALAIN GERALD · 2020 to 2025
$3.5M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00002 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN J · 2020 to 2025
$3.4M
NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003I
6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is the most common arrhythmia, affecting up to 6 million in the United States, and is associated with significant morbidity and mortality. Despite higher rates of AF clinical and social risk factors, underrepresented racial and ethnic group individuals have lower AF incidence. Structural factors, such as neighborhood-level racial and ethnic residential segregation, have been associated with incident cardiometabolic disease, particularly among underrepresented individuals. However, as data on segregation and incident AF are sparse our objective was to examine the association of segregation on AF.

methodsData from MESA (Multi-Ethnic Study of Atherosclerosis; baseline 2000-2002) were used to identify those with a diagnosis of AF during follow-up. Own-group racial and ethnic segregation was defined by local Gi* statistic, which compares the percentage of each racial and ethnic group in a current census tract to the surrounding area. Racial- and ethnic-stratified Cox proportional hazard models were used to estimate hazard ratios comparing across segregation levels. Models were adjusted for demographic, participant, and neighborhood level socioeconomic, and clinical factors.

resultsOur cohort comprised 5375 participants (31% Black, 25% Hispanic/Latino, 44% White). During a median follow-up of 16.6 years, 1035 participants (19.3%) were diagnosed with AF. Black and Hispanic/Latino participants had the highest prevalence of AF risk factors at baseline and were more likely to reside in segregated neighborhoods than White participants. After adjusting for demographic, socioeconomic, and clinical factors, neighborhood segregation was not found to be associated with AF across racial and ethnic groups.

conclusionsIn this longitudinal analysis we did not observe an association between residential segregation and AF incidence for Black, Hispanic/Latino, or White participants in fully adjusted models. Further research is needed to understand how individual factors may intersect with clinical, health care, and structural factors to drive previously described differential risk of AF.

Indexed as

AtherosclerosisAtrial FibrillationEthnicityNeighborhood CharacteristicsResidence CharacteristicsResidential SegregationAgedAged, 80 and overBlack or African AmericanFemaleHealth Status DisparitiesHispanic or LatinoHumansIncidenceMaleMiddle Agedatrial fibrillationdisparitiesepidemiologyhealth equitysegregation

Identifiers

PMID42333700
PMCPMC13477282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.