Observational studyJournal of the American Heart Association2026
Dynamic Risk Trajectories for Sudden Cardiac Arrest: The Role of Recurrent Cardiovascular Events.
Observational study in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
backgroundAlthough cardiovascular events increase sudden cardiac arrest (SCA) risk, the impact of recurrent events on subsequent SCA risk in a contemporary population is unknown. This study assessed whether patients with a first-time acute coronary syndrome (ACS) or heart failure (HF) hospitalization who experience a recurrent cardiovascular event have increased SCA risk.
methodsThe OSCAR (Observational Study of Cardiac Arrest Risk) is a prospective cohort with adjudicated SCA outcomes. The current study followed up patients who survived a first ACS or HF hospitalization (the index ACS or HF cohorts) for recurrent cardiovascular events and SCA. Recurrent event was a time-dependent variable in Cox models predicting SCA. Findings were validated in the FHS (Framingham Heart Study).
resultsAmong 2946 patients in the index ACS cohort, incidence of SCA was higher following a recurrent ACS event than without (3.70 versus 1.28 per 100 patient-years). A recurrent ACS event was associated with higher risk of SCA (adjusted hazard ratio [HR], 3.15 [95% CI, 2.06-4.83];
conclusionsRecurrent events were associated with higher risk of SCA; dynamic clinical trajectories of recurrent cardiovascular events may inform prevention of SCA.
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