Evidence map›Paper›PMID 42333509›Full record

ArticleThe Journal of international medical research2026

Inverse association between peripheral natural killer cells and thyroid autoimmunity in cases of miscarriage: Evidence from a cross-sectional study.

Xin Guo, Tingting Yang, Jinhong Wang, Xingming Zhong, Shuyun Zhao, Guanyou Huang

Abstract read
In one paragraph

Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin GuoReproductive Medicine Center, Department of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, China.
Tingting YangSchool of Public Health and Health Sciences, Guizhou Medical University, Key Laboratory of Environmental Pollution and Disease Monitoring, Ministry of Education, China.
Jinhong WangDepartment of Reproductive Medicine, Gui'an Branch of Guizhou Medical University Hospital, China.
Xingming ZhongReproductive Immunization Center, Guangdong Provincial Reproductive Science Institute, NHC Key Laboratory of Male Reproduction and Genetics, China.
Shuyun ZhaoReproductive Medicine Center, Department of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, China.
Guanyou HuangReproductive Medicine Center, Department of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, China.ORCID 0000-0003-0431-1845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo examine the association between the percentage of peripheral natural killer cells and thyroid autoimmunity in women with a history of miscarriage and assess whether B-cells mediate this association.MethodsThis retrospective cross-sectional study was conducted on 927 women with a history of miscarriage treated at the Affiliated Hospital of Guizhou Medical University (2021-2023). Peripheral T-cell, B-cell, and natural killer cell subsets and thyroid antibodies were assessed. Multivariable logistic regression, restricted cubic splines, and mediation analyses were performed.ResultsWomen with thyroid autoimmunity had lower percentage of peripheral natural killer cells and higher percentage of B-cells than those without thyroid autoimmunity (both

Indexed as

Abortion, SpontaneousAutoantibodiesAutoimmunityKiller Cells, NaturalThyroid GlandAdultB-LymphocytesCross-Sectional StudiesFemaleHumansIodide PeroxidasePregnancyRetrospective StudiesThyroglobulinT-Lymphocytesanti-thyroglobulinAutoantibodiesIodide PeroxidaseThyroglobulinB-cellsimmune mediationmiscarriageNatural killer cellsthyroid autoimmunity

Identifiers

PMID42333509
PMCPMC13305364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.