ArticleRegenerative biomaterials2026
A novel collagen hydrogel loaded with primary brown sugar for accelerating burn wound healing by a synergistic mechanism.
Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Severe skin burns present complex clinical challenges, including delayed healing and scar formation. As the first-extracted product of sugarcane, brown sugar has a long application history in Chinese traditional medicine. Inspired by its medicinal benefits, this study developed a collagen-based hydrogel co-loaded with brown sugar and epicatechin (COL-BS-EC) and evaluated its synergistic enhancement of therapeutic potential for promoting burn regenerative healing by comparison with comprehensive control groups and explored its relevant mechanisms involving the synergistic actions of non-sucrose components. Such a designed hydrogel showed potent species-selective antibacterial activity, particularly against
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