ArticleBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
A CURE for Microbiology Experiment: Isolation and Characterization of Antimicrobial-Producing Lactic Acid Bacteria From Fermented Sichuan Pickle Against Pathogenic Bacteria.
Article in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Traditional microbiology experimental teaching methodology, often based on rigid "cookbook" experiment plans, fails to meet the growing need to cultivate skilled and innovative individuals. Course-based undergraduate research experiences (CUREs) provide a solution by integrating research-based learning into the curriculum, offering an opportunity to improve the "hard" and "soft" skills for science, technology, engineering, and mathematics (STEM) students. In this study, a CURE was incorporated into the microbiology experiment curriculum focusing on the isolation and characterization of antimicrobial-producing lactic acid bacteria (LAB) from fermented Sichuan pickles. The CURE was divided into four key sections: (i) designing an experimental plan, (ii) isolation of LAB, (iii) evaluating the antibacterial effects and antibacterial active substances of LAB, and (iv) identifying LAB species and completing the experimental report. Through a tutor observation of the experiment process and a student questionnaire survey, the study demonstrated that CURE-based microbiology experiments significantly improved students' laboratory skills and microbiological-related experimental operation ability and nurtured their scientific thinking. This approach enhances students' preparedness for future career success and cultivates the growth of a well-rounded, skilled person in STEM disciplines.
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