ArticleScientific reports2026
Facilitators and barriers to medication adherence in systemic lupus erythematosus: a qualitative study in China.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medication adherence in systemic lupus erythematosus (SLE) remains suboptimal worldwide due to complex psychosocial and structural barriers. However, few studies have explored clinical experts' perspectives on facilitators and barriers to adherence, particularly within the Chinese healthcare context. This study aimed to explore clinical experts' perspectives on medication adherence among patients with SLE and to identify multidimensional factors influencing adherence. Semi-structured interviews were conducted with clinical experts and transcribed verbatim. Data were analysed using thematic analysis with NVivo 12. Themes were organized into five predefined dimensions: patient-related, disease-related, treatment-related, medical care-related, and socioeconomic-related factors. Each theme was classified as either a facilitator or a barrier. Visual analytic methods, including heatmaps, word clouds, frequency matrices, Sankey diagrams, and bipartite network graphs, were used to illustrate expert consensus and thematic relationships. A total of 38 themes were identified, including 18 facilitators and 20 barriers. All 16 experts identified symptom relief or mild disease, complex treatment regimens, distressing medication side effects, and high medication costs among the most frequently reported barriers. The most commonly reported facilitators included effectively managed side effects and personalized health education. Themes were unevenly distributed across dimensions, with a higher concentration of facilitators in medical care-related factors and a predominance of barriers within treatment-related factors. Variations in thematic emphasis may reflect differences in clinical roles and levels of patient engagement among experts. Medication adherence in patients with SLE is influenced by multiple interrelated factors. Improving adherence may benefit from comprehensive, multi-level strategies, including patient education, simplified treatment regimens, continuity of care, and supportive health policies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.