Evidence map›Paper›PMID 42331949›Full record

ArticleScientific reports2026

Prognostic analysis of epithelial ovarian cancer patients with normal CA125 level: a population-based comparative study.

Chuanzhong Liu, Liying Zhang, Yibao Huang, Haijuan Shi, Zhijun Yang

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chuanzhong LiuDepartment of Gynecological Oncology, Guangxi Medical University Cancer Hospital, No.71 Hedi Road, Nanning, 530021, Guangxi, China.
Liying ZhangDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yibao HuangDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Haijuan ShiDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Zhijun YangDepartment of Gynecological Oncology, Guangxi Medical University Cancer Hospital, No.71 Hedi Road, Nanning, 530021, Guangxi, China. yzj@sr.gxmu.edu.cn.

Funding

Guangxi Medical and Health Key Research Project No.201822Guangxi Zhuang Autonomous Region Key Laboratory of Automatic Detecting Technology and Instruments 2018-39Natural Science Foundation of Guangxi Province AD25069077
6 · The paper itself

Abstract

The epithelial ovarian cancer (EOC) with normal CA125 level is relatively rare. This study aims to develop a nomogram model for predicting the overall survival (OS) of EOC patients with normal CA125 level. A total of 13,068 patients with epithelial ovarian cancer (EOC) were extracted from the SEER database, and an additional 138 patients were recruited from our hospital as an external validation cohort. We found that the OEC patients with normal CA125 levels tend to have a better prognosis than those with elevated CA125 levels. Multivariate Cox regression analysis showed that age, summary stage, histology, and lymphadenectomy status were important factors affecting the prognosis of EOC patients with normal CA125 level.

Indexed as

CA-125 AntigenCarcinoma, Ovarian EpithelialOvarian NeoplasmsAdultAgedFemaleHumansMiddle AgedNeoplasm StagingNomogramsPrognosisProportional Hazards ModelsSEER ProgramCA-125 AntigenCA125 levelEpithelial ovarian cancerNomogramOverall survivalSEER database

Identifiers

PMID42331949
PMCPMC13562631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.