Evidence map›Paper›PMID 42331625›Full record

ArticleeNeuro2026

Development and Characterization of Conformation-Preferring Antibodies Targeting Phosphorylated Threonine 19 in PSD-95.

Jacob Alvarez, Prajwal Kurup, Lauren Kholsaat, Sai Kanuru, Esmeralda Paredes, Het Gor, Aliza J Bernardo, Bota Tulegenova, Kaetlyn S Khoury, Micaela Herrera and 2 more

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacob AlvarezDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Prajwal KurupDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Lauren KholsaatDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Sai KanuruDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Esmeralda ParedesDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Het GorDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Aliza J BernardoDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Bota TulegenovaDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Kaetlyn S KhouryDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Micaela HerreraDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Pedro CastrejonDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660.
Jary Y DelgadoDepartment of Biology, Loyola University Chicago, Chicago, Illinois 60660 jdelgadonunez@luc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activity-dependent synaptic plasticity is governed by posttranslational mechanisms that regulate the stability and molecular organization of postsynaptic protein complexes. Proline-directed phosphorylation of the N-terminus of PSD-95 promotes synaptic weakening during NMDAR-dependent LTD, yet this type of phosphorylation also alters the

Indexed as

AntibodiesDisks Large Homolog 4 ProteinMembrane ProteinsThreonineAnimalsCells, CulturedGlycogen Synthase Kinase 3 betaHippocampusHumansIntracellular Signaling Peptides and ProteinsNeuronsPhosphorylationProtein ConformationRatsAntibodiesDisks Large Homolog 4 ProteinDlg4 protein, ratGlycogen Synthase Kinase 3 betaIntracellular Signaling Peptides and ProteinsMembrane ProteinsThreoninecis–transisomerizationLTDphosphorylationproline-directed kinasesPSD-95

Identifiers

PMID42331625
PMCPMC13341226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.