Evidence map›Paper›PMID 42331573›Full record

ArticleBMJ open2026

Korean Medicine for Aging Cohort (KoMAC) study-a prospective multicentre cohort in urban and rural Korea: cohort profile.

Mi Mi Ko, Young-Eun Kim, Wonbae Ha, Seojae Jeon, Myunghwa Kim, So Young Jung, Kwang-Ho Choi, Geonhui Kang, Seungkwan Choi, Jungho Jo and 2 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mi Mi Ko *KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.ORCID http://orcid.org/0000-0002-5758-4655
Young-Eun Kim *KM Research Data Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.ORCID http://orcid.org/0000-0003-3327-2515
Wonbae HaDepartment of Korean Medicine Rehabilitation, College of Korean Medicine, Wonkwang University, Iksan, South Korea.
Seojae JeonKorea Institute of Integrative Medicine, Jangheung, South Korea.
Myunghwa KimKorea Institute of Integrative Medicine, Jangheung, South Korea.
So Young JungClinical Research Coordinating Team, Korea Institute of Oriental Medicine, Daejeon, South Korea.
Kwang-Ho ChoiKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.
Geonhui KangKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.
Seungkwan ChoiDepartment of Korean Medicine Rehabilitation, College of Korean Medicine, Wonkwang University, Iksan, South Korea.
Jungho JoDepartment of Korean Internal Medicine, College of Korean Medicine, Wonkwang University, Iksan, South Korea.
Junghan LeeKorea Institute of Integrative Medicine, Jangheung, South Korea milpaso@wku.ac.kr jjy0918@kiom.re.kr.ORCID http://orcid.org/0000-0002-7679-3946
Jeeyoun JungKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea milpaso@wku.ac.kr jjy0918@kiom.re.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe KoMAC (Korean Medicine for Aging Cohort) study investigates health characteristics related to ageing from both conventional and Korean medicine (KM) perspectives through a prospective, multicentre cohort study that also serves as a platform for future embedded intervention studies.

participantsThis study aimed to recruit 1000 adults aged 50-65 years from both urban (Iksan and surrounding areas, Jeonbuk Province) and rural (Jangheung and surrounding areas, Jeonnam Province) regions in Korea. Recruitment began in August 2023. The inclusion criteria were residence in the target region, literacy and written consent. FINDINGS TO DATE: Initial data showed regional differences in health behaviours and conditions; rural participants showed higher rates of alcohol consumption, smoking and childbirth experience among women, while urban participants showed lower pulmonary function and less favourable hearing thresholds. Ageing was associated with a general decline in physical and psychosocial function, particularly in women. KM-based phenotypic analysis revealed an age-related increase in kidney deficiency patterns and blood stasis, particularly in women. Emotional assessments indicated a decline in joy with age. Laboratory findings showed age-related increases in blood urea nitrogen levels in women, consistent with changes observed in KM-based phenotypes. FUTURE PLANS: The KoMAC study will continue with annual follow-ups, and blood samples will be collected again at the final follow-up visit to identify ageing-related risk factors. Embedded randomised controlled trials will evaluate the effects of KM-based interventions on health outcomes. TRIAL REGISTRATION NUMBER: Clinical Research Information Service (KCT0008863).

Indexed as

AgingHealth BehaviorMedicine, Korean TraditionalRural PopulationUrban PopulationAgedFemaleHealth StatusHumansMaleMiddle AgedProspective StudiesRepublic of KoreaAgingCOMPLEMENTARY MEDICINEFollow-Up StudiesGERIATRIC MEDICINEHealth SurveysPREVENTIVE MEDICINE

Identifiers

PMID42331573
PMCPMC13288976

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.