Evidence map›Paper›PMID 42331510›Full record

ArticleBMJ health & care informatics2026

Measuring performance trajectories in lung cancer surgery: a longitudinal study using the French national hospital database from 2020 to 2024.

Alain Bernard, Jonathan Cottenet, Pascale Tubert-Bitter, Catherine Quantin

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Article in BMJ health & care informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Alain BernardDepartment of Thoracic and Cardiovascular Surgery, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, France.ORCID http://orcid.org/0000-0002-5367-0097
Jonathan CottenetService de Biostatistiques et d'Information Médicale (DIM), Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, France.
Pascale Tubert-BitterHigh-Dimensional Biostatistics for Drug Safety and Genomics Paris-Saclay University, INSERM, Villejuif, France.
Catherine QuantinService de Biostatistiques et d'Information Médicale (DIM), Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, France catherine.quantin@chu-dijon.fr.ORCID http://orcid.org/0000-0001-5134-9411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLung cancer surgery is associated with significant postoperative morbidity (15%-40%) and mortality (2%-5%), with considerable interhospital variability. This study conducts the first national longitudinal analysis of performance trajectories in lung cancer surgery using advanced trajectory modelling approaches to understand temporal dynamics of quality evolution across hospitals.

methodsWe included all adult patients (French national hospital database, n=56 299; 148 hospitals) who underwent lung resection for primary lung cancer in 2020-2024. The primary outcome was severe complications including major postoperative complications and 30-day mortality. Annual logistic regression models incorporating clinical and procedural variables calculated risk-adjusted rates (RAR) for each hospital. Hospitals were classified using funnel plots corrected for overdispersion. Hidden Markov Models estimated transition probabilities between performance categories, while group-based multitrajectory models identified subgroups of hospitals sharing similar evolution profiles, stratified by activity volume (low, <43; medium, 43-100; high, >100 procedures/year).

resultsPredictive models demonstrated excellent stable discrimination (mean area under the ROC curve=0.890). Markov models revealed strong performance inertia (persistence probabilities ≥78%). Trajectory analysis identified a complex non-linear relationship between volume and quality. Medium-volume hospitals showed optimal improvement trajectories (45.4-45.8% RAR reduction). Conversely, some low-volume centres experienced catastrophic deterioration (843% RAR increase), while paradoxically, a subgroup of high-volume hospitals also showed concerning performance degradation (151% increase). DISCUSSION: This study demonstrates heterogeneous performance trajectories in French lung cancer surgery, challenging the assumption that high-volume alone guarantees quality and suggesting organisational complexity challenges.

conclusionThis study shows the value of implementing systematic outcome monitoring using existing administrative data to target quality improvement interventions and reduce inter-hospital performance variations.

Indexed as

HospitalsLung NeoplasmsAgedDatabases, FactualFemaleFranceHumansLongitudinal StudiesMaleMiddle AgedPostoperative ComplicationsData Interpretation, StatisticalGeneral SurgeryHealth Services ResearchHospital RecordsOutcome Assessment, Health Care

Identifiers

PMID42331510
PMCPMC13295999

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