Evidence map›Paper›PMID 42331435›Full record

ReviewAdvances in kidney disease and health2026

Ethical Perspectives in Renal Genetic Testing and Counseling.

Heather Gardiner, Dena Werner, Jessica Barker, Ilene L Hollin, Melody Slashinski, Laura Siminoff, Sarah Bauerle Bass, Ryan Blunt, Avrum Gillespie

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in kidney disease and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heather GardinerDepartment of Family Medicine, University at Buffalo, Buffalo, NY. Electronic address: hmm6@buffalo.edu.
Dena WernerDepartment of Family Medicine, University at Buffalo, Buffalo, NY.
Jessica BarkerDepartment of Social and Behavioral Sciences, Temple University, Philadelphia, PA.
Ilene L HollinHealth Services Administration and Policy, Temple University, Philadelphia, PA.
Melody SlashinskiHealth Services Administration and Policy, Temple University, Philadelphia, PA.
Laura SiminoffDepartment of Social and Behavioral Sciences, Temple University, Philadelphia, PA.
Sarah Bauerle BassDepartment of Social and Behavioral Sciences, Temple University, Philadelphia, PA.
Ryan BluntDepartment of Social and Behavioral Sciences, Temple University, Philadelphia, PA.
Avrum GillespieLewis Katz School of Medicine, Temple University Health, Philadelphia, PA.

Funding

Genetic Testing (APOL1) Decisional Support for Potential Living Kidney DonorsR01DK131016 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI GARDINER, HEATHER MARIE · 2021 to 2024
$2.3M
NIDDK NIH HHS R01 DK131016
6 · The paper itself

Abstract

This report examines ethical considerations surrounding genetic testing in nephrology. More than 14% of the U.S. population lives with CKD, including approximately 800,000 individuals receiving treatment for end-stage kidney disease, and an estimated 20% of CKD cases have a genetic etiology. As genetic testing becomes integrated into routine care, careful evaluation of its risks and benefits is essential. Using the Georgetown principles-autonomy, beneficence, nonmaleficence, and justice-as a framework, we analyze contemporary ethical challenges in renal genetics. We emphasize the importance of shared decision-making, culturally and linguistically appropriate risk communication, and access to genetic counseling. Finally, we offer practical recommendations to strengthen ethical implementation and advance equitable integration of genomic medicine in nephrology.

Indexed as

Genetic CounselingGenetic TestingKidney Failure, ChronicNephrologyRenal Insufficiency, ChronicDecision Making, SharedHumansPersonal AutonomyChronic kidney diseaseEnd-stage kidney diseaseEthicsGeneticsGenetic testing

Identifiers

PMID42331435
PMCPMC13692788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.