ArticleJournal of acquired immune deficiency syndromes (1999)2026
Indirect Effects of HIV Differentiated Service Delivery Programmes on Quality of Clinic Care: A Retrospective Cohort Study of Clients Starting Antiretroviral Therapy.
Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
backgroundAlthough the benefits for clients collecting antiretroviral therapy (ART) through differentiated service delivery programmes (DSD) have been described, there are limited data on whether DSD indirectly benefits clients ineligible for DSD, by allowing more clinic resources to be redirected toward them.
settingDe-identified, routinely-collected data from 112 clinics in KwaZulu-Natal, South Africa were analyzed.
methodsUsing generalized linear mixed effects regression, we assessed whether the quality of care provided to clients initiating ART (and therefore ineligible for DSD) improved after increases in the proportion of clients in their clinic referred to DSD. Quality-of-care outcomes were the probability of clients having a CD4 count test, having a 6-month viral load (VL) test and being retained for 6 months.
resultsBetween February 2022 and September 2023, a total of 36,865 clients initiated ART. Among those in each outcome analysis, 77% had CD4 count results, 72% had 6-month VL results, and 70% were retained for 6 months. We found a positive relationship between the clinic DSD referral proportion and test completion among newly initiated clients, although this was only weakly significant for CD4 count; when DSD referrals increased from 20% to 30%, the probability of having a CD4 count and VL test increased by 0.97% (95% CI: -0.27 to 2.58%) and 1.35% (95% CI: 0.11 to 2.95%), respectively. We found no evidence of an association with DSD and retention.
conclusionsIn the first study of this topic, increases in clinic DSD referrals were associated with small improvements in care. With full DSD scale-up, programmatically meaningful effects could be achieved.
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