ArticleProceedings (Baylor University. Medical Center)2026
Nationwide analysis of adult nongonococcal native septic knee arthritis hospitalizations from 2016 to 2022.
Article in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Nationwide analysis of adult nongonococcal septic knee arthritis hospitalizations from 2016 to 2022.Proceedings (Baylor University. Medical Center) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeptic arthritis (SA) is a medical emergency associated with substantial morbidity and mortality. Although the knee is the most commonly affected joint in adults, contemporary national data describing characteristics, mortality, and healthcare utilization in knee-specific native SA are limited.
methodsWe conducted a retrospective study of adult hospitalizations for nongonococcal native knee SA in the United States using the National Inpatient Sample database from 2016 to 2022. Hospitalizations were identified using ICD-10 diagnostic codes, excluding gonococcal and prosthetic joint infections. Thus, the analytic cohort was restricted to native joint disease and did not include prosthetic joint infection. Weighted analyses were performed to generate national estimates. Multivariable logistic regression was used to identify factors independently associated with in-hospital mortality.
resultsAmong approximately 205 million adult hospitalizations, 92,290 (0.045%) had native SA of the knee. In-hospital mortality was 2.5%. Patients who died were older, had longer lengths of stay, and incurred more than double the median hospital charges compared with survivors. In multivariable analysis, factors independently associated with higher odds of in-hospital death included respiratory failure (odds ratio [OR] 8.54), sepsis (OR 3.57), liver disease (OR 3.45), cerebrovascular disease (OR 2.27), acute kidney injury (OR 2.05), chronic kidney disease (OR 1.66), myocardial infarction (OR 1.60), heart failure (OR 1.55), and increasing age. Survivors demonstrated substantial postacute care needs, with 36% discharged to skilled nursing or intermediate care facilities.
conclusionsIn this nationally representative cohort, nongonococcal native septic knee arthritis showed substantial in-hospital mortality, morbidity, and healthcare utilization. Mortality was driven primarily by multiorgan dysfunction rather than demographic or socioeconomic factors. Early identification and aggressive management of high-risk patients may improve outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.