SynthesisProceedings (Baylor University. Medical Center)2026
Comparing the diagnostic performance of 19-gauge and 22-gauge needles in endoscopic ultrasound-guided liver biopsy: a systematic review and meta-analysis.
Synthesis in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Endoscopic ultrasound-guided liver biopsy: refining a new approach.Proceedings (Baylor University. Medical Center) · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLiver biopsy is the gold standard for histologic diagnosis of parenchymal liver disease. Endoscopic ultrasound-guided liver biopsy (EUS-LB) is increasingly being performed for tissue acquisition. However, the needle size to perform the procedure is still debated. We performed a systematic review and meta-analysis comparing outcomes and safety of two different needles, 19 gauge (G) and 22 G, for EUS-LB.
methodsA comprehensive search of multiple databases was conducted to identify studies comparing 19 G and 22 G needles for liver biopsy. Studies reporting tissue adequacy, histologic diagnosis, and other relevant outcomes were included. A meta-analysis was conducted using random-effects models, and heterogeneity was assessed using standard methods.
resultsOur analysis of six studies revealed the superiority of 19 G needles in terms of tissue adequacy (odds ratio [OR] 7.9, 95% confidence interval [CI] 1.9-32.0,
conclusionOur meta-analysis supports the preferential use of 19 G needles over 22 G needles for EUS-LB, given their superior performance in tissue adequacy and histological diagnosis with no difference in postprocedural adverse events. These findings underscore the importance of appropriate needle size in optimizing EUS-LB outcomes.
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