Evidence map›Paper›PMID 42329866›Full record

ArticlePloS one2026

Outcomes of In-hospital Cardiac Arrest: Insights from a Medical Intensive Care Unit.

Karthik Kailasam, Mahmoud Alwakeel, Xiaofeng Wang, Abhijit Duggal, Sudhir Krishnan

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karthik KailasamInternal Medicine, University of Arizona-College of Medicine Phoenix, Phoenix, Arizona, United States of America.ORCID https://orcid.org/0000-0001-7300-3251
Mahmoud AlwakeelCritical Care Medicine, Duke university health system, Durham, North Carolina, United States of America.
Xiaofeng WangRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America.ORCID https://orcid.org/0000-0001-8212-6931
Abhijit DuggalRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America.
Sudhir KrishnanRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritically ill patients admitted to intensive care units (ICU) usually suffer from life-threatening illnesses, and many are hemodynamically unstable. The incidence of cardiac arrest in the ICU is approximately 22 per 1000 admissions, and survival to discharge after in-hospital cardiac arrest (IHCA) is approximately 14%. Variables associated with IHCA survival are poorly understood and the outcomes of cardiopulmonary resuscitation (CPR) in the ICU are poorly reported in the literature. We investigated the characteristics of IHCA and factors that are associated with poor IHCA survival. METHODS AND

findingsAfter adjusting for age, APACHE III score, and initial rhythm, every one-minute increase in CPR duration was associated with 1.161 (95% CI 1.119-1.204; p < 0.0001) odds of death during resuscitation and 1.154 (95% CI 1.059-1.258; p < 0.0001) odds of death at the time of ICU discharge. Hospital survivors had a lower APACHE III score (Mean = 88.3, SD 29.8, IQR 66-106) and acute physiology score (Mean = 75, SD 30, IQR 56-94) compared to non-survivors. Hospital survivors were also more likely than non-survivors to have a shockable rhythm at the time of arrest (20% versus 7.5%), shorter average CPR duration (5.4 minutes versus 12.8 minutes), longer length of ICU stay (14 days versus 1.8 days) and longer length of hospital stay (25 days versus 6.1 days).

conclusionBased on our retrospective analysis, we conclude that the odds of IHCA mortality is directly proportional to the duration of CPR regardless of age, initial rhythm, and severity of underlying illness.

Indexed as

Heart ArrestIntensive Care UnitsAgedAPACHECardiopulmonary ResuscitationFemaleHospital MortalityHumansMaleMiddle AgedTreatment Outcome

Identifiers

PMID42329866
PMCPMC13286161

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