Evidence map›Paper›PMID 42329436›Full record

ArticleEuropean journal of ageing2026

Stress and mental health in older adulthood: testing linear dose-response and steeling effects of early-life adversity.

Myriam V Thoma, Jan Höltge, Simona-Viktoria Balsiger, Florence Bernays, Shauna L Rohner

Abstract read
In one paragraph

Article in European journal of ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Myriam V ThomaPsychopathology and Clinical Intervention, Institute of Psychology, University of Zurich, Binzmühlestrasse 14/17, 8050, Zurich, Switzerland. myriam.thoma@unibas.ch.ORCID http://orcid.org/0000-0003-4316-522X
Jan HöltgeResilience Research Centre, Dalhousie University, Halifax, NS, Canada.ORCID https://orcid.org/0000-0002-8328-0129
Simona-Viktoria BalsigerPsychopathology and Clinical Intervention, Institute of Psychology, University of Zurich, Binzmühlestrasse 14/17, 8050, Zurich, Switzerland.
Florence BernaysDepartment of Business Administration, Chair of Human Resource Management and Leadership, University of Zurich, Plattenstrasse 14, 8032, Zurich, Switzerland.
Shauna L RohnerPsychopathology and Clinical Intervention, Institute of Psychology, University of Zurich, Binzmühlestrasse 14/17, 8050, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-8273-0987

Funding

Schweizerischer Nationalfonds 407640_177355/1Swiss Government Excellence ESKAS-Nr. 2016.0109
6 · The paper itself

Abstract

Although mental health in later life has gained increasing attention, research on how early-life adversity (ELA) affects older adults remains limited. This study examined whether ELA exposure relates to mental health via a linear dose-response effect or a curvilinear association as proposed by the Steeling Effect Theory. ELA and past-year mental health disorders were assessed in N = 211 older adults (M = 69.8 years; 46.4% female), including a high-risk group with substantial ELA (RG; n = 100) and a lower-risk control group (CG; n = 111). Linear and curvilinear associations were tested using negative binomial generalized linear models. Overall, 59.2% of participants met criteria for at least one past-year mental health disorder (RG: 68.0%; CG: 51.4%). Higher levels of ELA were associated with an increased number of mental health disorders (1.5% per unit increase), supporting a linear dose-response effect. No evidence was found for a curvilinear (steeling) effect. Findings underscore the long-term impact of early-life stress on mental health in older adulthood. In this sample, a linear model better characterized the association between ELA and past-year mental health disorder count than a curvilinear model. These findings are consistent with the importance of preventing and reducing ELA as part of broader efforts to support mental health across the life course.

Indexed as

Dose–responseEarly-life adversityMental health morbidityOlder adulthoodSteeling

Identifiers

PMID42329436
PMCPMC13538305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.