In one paragraphArticle in Glycoconjugate journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Francisco Glerison da Silva NascimentoLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil.ORCID 0000-0003-2481-5733 Pedro Henrique de Souza Ferreira BringelLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil.ORCID 0000-0001-6278-2755 Diego Freitas de AraujoLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil.ORCID 0009-0009-5226-2858 Mário Rogério Lima MotaLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil.ORCID 0000-0003-3778-0584 Maria Gleiciane de Queiroz MartinsLaboratório de Moléculas Biologicamente Ativas (BioMol-Lab), Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, s/n; Bloco 907, Fortaleza, CE, 60455-970, Brazil.ORCID 0000-0001-6966-8840 Mayara Torquato Lima da SilvaLaboratório de Moléculas Biologicamente Ativas (BioMol-Lab), Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, s/n; Bloco 907, Fortaleza, CE, 60455-970, Brazil.ORCID 0000-0001-7420-5306 Clareane Avelino Simplício NobreLaboratório de Moléculas Biologicamente Ativas (BioMol-Lab), Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, s/n; Bloco 907, Fortaleza, CE, 60455-970, Brazil.ORCID 0000-0003-1865-2915 Benildo Sousa CavadaLaboratório de Moléculas Biologicamente Ativas (BioMol-Lab), Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, s/n; Bloco 907, Fortaleza, CE, 60455-970, Brazil.ORCID 0000-0002-5791-6170 Kyria Santiago do NascimentoLaboratório de Moléculas Biologicamente Ativas (BioMol-Lab), Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, s/n; Bloco 907, Fortaleza, CE, 60455-970, Brazil.ORCID 0000-0002-2220-4552 Rondinelle Ribeiro CastroLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil.ORCID 0000-0002-9399-4109 Ana Maria Sampaio AssreuyLaboratório de Fisio-Farmacologia da Inflamação (LAFFIN), Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Dr. Silas Munguba 1700, Fortaleza, CE, 60714-903, Brazil. ana.assereuy@uece.br.ORCID 0000-0002-2323-5385 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Previous study demonstrated that Hypnea cervicornis lectin (HCA) reduces inflammation and nociception via interaction with the lectin carbohydrate-binding site, modulating gene expression of the interleukins IL-1β, TNF-α and of iNOS. This study evaluated the effect of HCA in the rat model of arthritis induced by zymosan in the tibiotarsal joint and the involvement of macrophage-derived mediators. In vitro, macrophages were stimulated with zymosan before being incubated with HCA and the supernatant was injected into the joint. In vivo, HCA was administered by intravenous route after intra-articular injection of zymosan, fMLP, or macrophages supernatant. Hypernociception, edema and leukocyte influx were evaluated in the joints, and inflammatory mediators in the macrophage supernatant or periarticular tissue. In vitro, HCA (100 µg/ml) reduced NO
Indexed as
Anti-Inflammatory AgentsArthritis, ExperimentalLectinsMacrophagesAnimalsInterleukin-1betaMaleNitric Oxide Synthase Type IIRatsRats, WistarRhodophytaSeaweedZymosanAnti-Inflammatory AgentsInterleukin-1betaLectinsNitric Oxide Synthase Type IIZymosanAlgae lectinCytokineHCAJoint inflammation
Identifiers
PMID42329431
PMCPMC13287125
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