Evidence map›Paper›PMID 42329365›Full record

ReviewHNO2026

[Facial fillers: evidence base, anatomical principles, materials, risks, techniques, and future perspectives].

Chrisanthi Karapantzou, Martin Canis

Abstract readReviewEnglish Abstract
PubMed Publisher
In one paragraph

Review in HNO, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chrisanthi KarapantzouHNO-Universitätsklinik LMU, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland. chrisanthi24@yahoo.gr.
Martin CanisHNO-Universitätsklinik LMU, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of dermal fillers has emerged over the past two decades as one of the fastest-growing interventions in aesthetic medicine. While hyaluronic acid-based fillers account for the largest market share, alternative materials such as calcium hydroxylapatite, poly-L-lactic acid, and polymethylmethacrylate-based products are gaining increasing importance. Advances in injection strategies, anatomical precision, rheological product differentiation, and safety standards have led to a marked improvement in clinical outcomes. However, the profile of rare but potentially severe complications-particularly vascular occlusions-remains a central challenge. The aim of this review is to provide a comprehensive, evidence-based analysis of the current literature regarding materials, mechanisms of action, anatomical risk zones, injection techniques, indications, complication management, and future developments in filler therapy.

Indexed as

Cosmetic TechniquesDermal FillersEvidence-Based MedicineFaceHumansInjections, SubcutaneousRejuvenationDermal FillersCosmetic techniquesFaceHyaluronic acidInjectablesRejuvenation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.